mp3®

  • mp3
  • mp3
  • mp3
  • mp3
  • mp3
  • mp3
  • mp3
Case Reports
Publications
Videos
  • Tissue origin :
    Cortico-cancellous heterologous bone mix
  • Tissue collagen :
    Preserved plus an additional 10% collagen gel
  • Physical form :
    Pre-hydrated granules and collagen gel
  • Composition :
    90% granulated mix, 10% collagen gel
  • Granulometry :
    600-1000 µm
  • Re-entry time :
    About 5 months
  • Packaging :
    Syringe: 1.0 cc, 3 x 0.25 cc, 3 x 0.5 cc, 3 x 1.0 cc
  • Product codes :
    A3005FS | 1 Syringe | 1.0 cc | Porcine
    A3005FE | 1 Syringe | 1.0 cc | Equine
    A3075FS | 3 Syringes | 3x0.25 cc | Porcine
    A3015FS | 3 Syringes | 3x0.5 cc | Porcine
    A3015FE | 3 Syringes | 3x0.5 cc | Equine
    A3030FS | 3 Syringes | 3x1.0 cc | Porcine
    A3030FE | 3 Syringes | 3x1.0 cc | Equine
  • GMDN code : 38746
Characteristics
mp3® is a heterologous origin biomaterial made of 600-1000 µm pre-hydrated collagenated cortico-cancellous granules, properly mixed with collagen gel. Thus, it is possible both skipping the hydration phase and decreasing the risk of accidental exposure of material to pathogens during manipulation and grafting phases; furthermore the syringe is flexible and ideal to simplify grafting in the receiving site.
The granules are endowed with characteristics very similar to human mineral bone1, and can be used as an alternative to autologous bone.
Their natural micro-porous consistency facilitates new bone tissue formation in defect sites and accelerates the regeneration process.
Gradually resorbable2, it preserves the original graft shape and volume (osteoconductive property)3,4,5. Moreover, thanks to its collagen content, the product facilitates blood clotting and the subsequent invasion of repairing and regenerative cells.
Handling
mp3® is available in ready-to-use syringes and can be easily grafted avoiding the hydration and manipulation phases.
After adapting the material to the defect shape, it is necessary to remove non stable residues before proceeding to soft tissue suture.
Clinical indications
The Tecnoss® patented manufacturing process used to obtain OsteoBiol® materials is able to achieve biocompatibility preserving part of the collagen matrix of the animal bone6 and avoiding at the same time high temperatures that would cause ceramization of the granules: the result is a unique biomaterial, consisting of mineral component and organic matrix, with a porous surface extremely similar to autogenous bone and able to resorb progressively while new bone formation takes place2.
mp3®, a pre-hydrated cortico-cancellous bone mix with 10% collagen gel, has been developed with this innovative biotechnology and is a "ready-to-use" product.
mp3® main indication is lateral access maxillary sinus lift3,7,8, always in association with Evolution membranes, recommended to cover the antrostomy: the mp3® syringe can be directly applied into the bony window without having to mix the mp3® granules with saline.
Due to its collagen gel content, mp3® allows an excellent graft stability while its hydrophilia guarantees quick blood absorption and therefore the necessary graft vascularization. mp3® has also been successfully used in combination with Evolution membranes for alveolar ridge preservation9: the application of this biomaterial significantly limits the alveolar ridge width and height reduction that would naturally occur with spontaneous healing, preserving thus the alveolar ridge volume and allowing a correct second stage implant placement.
Finally, mp3® is also indicated for horizontal augmentation (two wall defects) in combination with autogenous bone blocks10 or with OsteoBiol® Lamina11: its cortico-cancellous composition allows a progressive resorption of osteoclastic type, and in parallel a similar rate of new bone formation2.
These unique properties allow a very good graft volume preservation, a healthy new bony tissue and ultimately, a successful implant rehabilitation.
Bibliography
1 BARONE A, RICCI M, COVANI U, NANNMARK U, AZARMEHR I, CALVO GUIRADO JL
MAXILLARY SINUS AUGMENTATION USING PREHYDRATED CORTICOCANCELLOUS PORCINE BONE: HYSTOMORPHOMETRIC EVALUATION AFTER 6 MONTHS
CLIN IMPLANT DENT RELAT RES, 2012 JUN;14(3):373-9 EPUB 2010 MAY 11

2 NANNMARK U, SENNERBY L
THE BONE TISSUE RESPONSES TO PREHYDRATED AND COLLAGENATED CORTICO-CANCELLOUS PORCINE BONE
GRAFTS: A STUDY IN RABBIT MAXILLARY DEFECTS
CLIN IMPLANT DENT RELAT RES, 2008 DEC;10(4):264-70. EPUB 2008 JAN 30

3 RAMIREZ FERNANDEZ MP, CALVO GUIRADO JL, MATÉ SANCHEZ DE VAL JE, DELGADO RUIZ RA, NEGRI B, BARONA DORADO C
ULTRASTRUCTURAL STUDY BY BACKSCATTERED ELECTRON IMAGING AND ELEMENTAL MICROANALYSIS OF BONE-TO-BIOMATERIAL INTERFACE AND MINERAL DEGRADATION OF PORCINE XENOGRAFTS USED IN MAXILLARY SINUS FLOOR ELEVATION
CLIN ORAL IMPLANTS RES, 2012 JAN 26, EPUB AHEAD OF PRINT

4 CALVO GUIRADO JL, RAMIREZ FERNANDEZ MP, NEGRI B, DELGADO RUIZ RA, MATÉ SANCHEZ DE VAL JE, GOMEZ MORENO G
EXPERIMENTAL MODEL OF BONE RESPONSE TO COLLAGENIZED XENOGRAFTS OF PORCINE ORIGIN (OSTEOBIOL® mp3): A
RADIOLOGICAL AND HISTOMORPHOMETRIC STUDY
CLIN IMPLANT DENT RELAT RES, 2013 FEB;15(1):143-51 EPUB 2011 MAR 31

5 RAMIREZ FERNANDEZ MP, CALVO GUIRADO JL, DELGADO RUIZ RA, MATÉ SANCHEZ DE VAL JE, VICENTE ORTEGA V, MESEGUER OLMOS L
BONE RESPONSE TO HYDROXYAPATITES WITH OPEN POROSITY OF ANIMAL ORIGIN (PORCINE OSTEOBIOL® mp3) AND BOVINE (ENDOBON®): A RADIOLOGICAL AND HISTOMORPHOMETRIC STUDY
CLIN ORAL IMPLANTS RES, 2011 JUL; 22(7):767-73

6 FIGUEIREDO M, HENRIQUES J, MARTINS G, GUERRA F, JUDAS F, FIGUEIREDO H
PHYSICOCHEMICAL CHARACTERIZATION OF BIOMATERIALS COMMONLY USED IN DENTISTRY AS BONE SUBSTITUTES -
COMPARISON WITH HUMAN BONE
J BIOMED MATER RES B APPL BIOMATER, 2010 FEB; 92(2):409-19

7 SILVESTRI M, MARTEGANI P, D'AVENIA F, FARNETI M, CAPRI D, PAOLANTONI G, LANDI L
SIMULTANEOUS SINUS AUGMENTATION WITH IMPLANT PLACEMENT: HISTOMORPHOMETRIC COMPARISON OF TWO
DIFFERENT GRAFTING MATERIALS. A MULTICENTER DOUBLEBLIND PROSPECTIVE RANDOMIZED CONTROLLED CLINICAL TRIAL
INT J ORAL MAXILLOFAC IMPLANTS, 2013 MAR-APR;28(2):543-9

8 PAGLIANI L, ANDERSSON P, LANZA M, NAPPO A, VERROCCHI D, VOLPE S, SENNERBY L
A COLLAGENATED PORCINE BONE SUBSTITUTE FOR AUGMENTATION AT NEOSS IMPLANT SITES: A PROSPECTIVE 1-YEAR
MULTICENTER CASE SERIES STUDY WITH HISTOLOGY
CLIN IMPLANT DENT RELAT RES, 2012 OCT;14(5):746-58 EPUB 2010 OCT 26

9 BARONE A, ALDINI NN, FINI M, GIARDINO R, CALVO GUIRADO JL, COVANI U
XENOGRAFT VERSUS EXTRACTION ALONE FOR RIDGE PRESERVATION AFTER TOOTH REMOVAL: A CLINICAL AND HISTOMORPHOMETRIC STUDY
J PERIODONTOL, 2008 AUG;79(8):1370-7

10 BARONE A, COVANI U
MAXILLARY ALVEOLAR RIDGE RECONSTRUCTION WITH NONVASCULARIZED AUTOGENOUS BLOCK BONE: CLINICAL RESULTS
J ORAL MAXILLOFAC SURG, 2007, 65:2039-2046

11 WACHTEL H, FICKL S, HINZE M, BOLZ W, THALMAIR T
THE BONE LAMINA TECHNIQUE: A NOVEL APPROACH FOR LATERAL RIDGE AUGMENTATION - A CASE SERIES
INT J PERIODONTICS RESTORATIVE DENT, 2013 JUL-AUG;33(4):491-7
© 2017 Copyright by Tecnoss Dental Srl. P.I. 08917490016. All rights reserved.. Web Site producted by DSI Design