Apatos

  • Apatos
  • Apatos
Case Reports
Publications
Videos
  • Tissue origin :
    Heterologous cortico-cancellous bone mix
  • Tissue collagen :
    Degraded
  • Physical form :
    Radiopaque granules of mineral hydroxyapatite
  • Composition :
    100% cortico-cancellous mix
  • Granulometry :
    1000-2000 µm
  • Re-entry time :
    About 5 months
  • Packaging :
    Vial: 1.0 g
  • Product codes :
    A0210FS | 1 Vial | 1.0 g | Porcine
    A0210FE | 1 Vial | 1.0 g | Equine
  • GMDN code : 38746
Characteristics
Apatos is a biocompatible1, osteoconductive2 biomaterial of heterologous origin with characteristics similar to mineralized human bone3,4; it can therefore be used as alternative to autologous bone. The natural microporous consistency of Apatos facilitates the formation of new bone tissue in bone defect area5, accelerating the process. Apatos nanocrystalline hydroxyapatite is a mix of cortical and cancellous bone granules.
Handling
Apatos must always be hydrated and thoroughly mixed with a few drops of sterile saline; it can also be mixed with patient's blood. Finally it can be mixed if necessary with the drug selected for surgery; the mixture thus obtained should be positioned with a sterile spatula or syringe for biomaterials.
Clinical indications
Filler of large maxillofacial bone defects, reconstruction or corrections in non-load-bearing indications, Apatos may be used as a drug-carrier.
Bibliography
1 TRUBIANI O, SCARANO A, ORSINI G, DI IORIO D, D'ARCANGELO C, PICCIRILLI M, SIGISMONDO M, CAPUTI S
THE PERFORMANCE OF HUMAN PERIODONTAL LIGAMENT MESENCHYMAL STEM CELLS ON XENOGENIC BIOMATERIALS
INT J IMMUNOPATHOL PHARMACOL, 2007 JAN-MAR; 20(1 SUPPL 1):87-91

2 BRUNELLI G, SOLLAZZO V, CARINCI F, PALMIERI A, GIRARDI A, MONGUZZI R
OSTEOBIOL® INFLUENCES OSTEOGENIC DIFFERENTIATION OF ADIPOSE DERIVED STEM CELLS
EUR J INFLAMM, 2011, VOL. 9, NO. 3(S), 103-107
3 ORSINI G, SCARANO A, PIATTELLI M, PICCIRILLI M, CAPUTI S, PIATTELLI A
HISTOLOGIC AND ULTRASTRUCTURAL ANALYSIS OF REGENERATED BONE IN MAXILLARY SINUS AUGMENTATION USING A PORCINE BONE-DERIVED BIOMATERIAL
J PERIODONTOL 2006 DEC;77(12):1984-90

4 SCARANO A, PIATTELLI A, PERROTTI V, MANZON L, IEZZI G
MAXILLARY SINUS AUGMENTATION IN HUMANS USING CORTICAL PORCINE BONE: A HISTOLOGICAL AND HISTOMORPHOMETRICAL EVALUATION AFTER 4 AND 6 MONTHS
CLIN IMPLANT DENT RELAT RES, 2011 MAR; 13(1):13-18

5 IEZZI G, DEGIDI M, PIATTELLI A, MANGANO C, SCARANO A, SHIBLI JA, PERROTTI V
COMPARATIVE HISTOLOGICAL RESULTS OF DIFFERENT BIOMATERIALS USED IN SINUS AUGMENTATION PROCEDURES: A HUMAN STUDY AT 6 MONTHS
CLIN ORAL IMPLANTS RES, 2012 DEC;23(12):1369-76 EPUB 2011 NOV 2
© 2017 Copyright by Tecnoss Dental Srl. P.I. 08917490016. All rights reserved.. Web Site producted by DSI Design