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Tissue origin :
Heterologous cortico-cancellous bone mix
Tissue collagen :
Preserved plus an additional 10% collagen gel
Physical form :
Pre-hydrated granules and collagen gel
Composition :
90% granulated mix, 10% collagen gel
Granulometry :
600-1000 µm
1000- 2000 µm
Re-entry time :
About 5 months
Packaging :
Syringe: 2.0 cc
Product codes :
600-1000 µm
A3010FS | 1 Syringe | 2.0 cc | Porcine
A3010FE | 1 Syringe | 2.0 cc | Equine

1000-2000 µm
A3210FS | 1 Syringe | 2.0 cc | Porcine
A3210FE | 1 Syringe | 2.0 cc | Equine
GMDN code : 46425

Characteristics: mp3® is a heterologous origin biomaterial made of 600-1000 µm or 1000-2000 µm pre-hydrated collagenated cortico-cancellous granules, properly mixed with collagen gel. Thus, it is possible both skipping the hydration phase and decreasing the risk of accidental exposure of material to pathogens during manipulation and grafting phases; furthermore the syringe is flexible and ideal to simplify grafting in the receiving site. The granules are endowed with characteristics very similar to human mineral bone¹, and can be used as an alternative to autologous bone.
Their natural micro-porous consistency facilitates new bone tissue formation in defect sites and accelerates the regeneration process. Gradually resorbable², it preserves the original graft shape and volume (osteoconductive property)^3,4,5.
Moreover, thanks to its collagen content, the product facilitates blood clotting and the subsequent invasion of repairing and regenerative cells.
Handling: mp3® is available in ready-to-use syringes and can be easily grafted avoiding the hydration and manipulation phases. After adapting the material to the defect shape, it is necessary to remove non stable residues before proceeding to soft tissue suture.
Clinical information: Filler of bone defects after trauma, reconstruction or corrections in non-load-bearing indications. mp3® can be used as drug carrier.
Bibliography: ¹ FIGUEIREDO M, HENRIQUES J, MARTINS G, GUERRA F, JUDAS F, FIGUEIREDO H
PHYSICOCHEMICAL CHARACTERIZATION OF BIOMATERIALS COMMONLY USED IN DENTISTRY AS BONE SUBSTITUTES - COMPARISON WITH HUMAN BONE
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B: APPLIED BIOMATERIALS, 2010FEB; 92(2):409-19

² NANNMARK U, SENNERBY L
THE BONE TISSUE RESPONSES TO PREHYDRATED AND COLLAGENATED CORTICO-CANCELLOUS PORCINE BONE GRAFTS: A STUDY IN RABBIT MAXILLARY DEFECTS
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, 2008 DEC;10(4):264-70. EPUB 2008 JAN 30

³ RAMIREZ FERNANDEZ MP, CALVO GUIRADO JL, MATÉ SANCHEZ DE VAL JE, DELGADO RUIZ RA, NEGRI B, BARONA DORADO C
ULTRASTRUCTURAL STUDY BY BACKSCATTERED ELECTRON IMAGING AND ELEMENTAL MICROANALYSIS OF BONE-TO-BIOMATERIAL INTERFACE AND MINERAL DEGRADATION OF PORCINE XENOGRAFTS USED IN MAXILLARY SINUS FLOOR ELEVATION
CLIN ORAL IMPLANTS RES, 2012 JAN 26, EPUB AHEAD OF PRINT

⁴ CALVO GUIRADO JL, RAMIREZ FERNANDEZ MP, NEGRI B, DELGADO RUIZ RA, MATÉ SANCHEZ DE VAL JE, GOMEZ MORENO G
EXPERIMENTAL MODEL OF BONE RESPONSE TO COLLAGENIZED XENOGRAFTS OF PORCINE ORIGIN (OSTEOBIOL® mp3): A RADIOLOGICAL AND HISTOMORPHOMETRIC STUDY
CLIN IMPLANT DENT RELAT RES, 2013 FEB;15(1):143-51 EPUB 2011 MAR 31

⁵ RAMIREZ FERNANDEZ MP, CALVO GUIRADO JL, DELGADO RUIZ RA, MATÉ SANCHEZ DE VAL JE, VICENTE ORTEGA V, MESEGUER OLMOS L
BONE RESPONSE TO HYDROXYAPATITES WITH OPEN POROSITY OF ANIMAL ORIGIN (PORCINE OSTEOBIOL® mp3) AND BOVINE (ENDOBON®): A RADIOLOGICAL AND HISTOMORPHOMETRIC STUDY
CLIN ORAL IMPLANTS RES, 2011 JUL; 22(7):767-73

mp3®